When an armed thief, whom Peter had encountered earlier and refused to stop out of spite, later murders his foster father/uncle in a robbery, a guilt-ridden Peter is later driven to use his abilities to atone for his partial responsibility in his uncle's murder, as the costumed vigilante Spider-Man.
While attending a field trip to a scientific corporation, he is bitten by a genetically-modified spider and as a result, begins to develop spider-like superpowers, including enhanced strength, speed, agility, stamina, durability and reflexes, along with the ability to crawl solid surfaces and a sixth sense, which warns him of imminent danger, all of which he decides to utilize for personal gain. Orphaned at the age of six, Peter Parker is an outcast and withdrawn teenaged science prodigy, who lives in Queens, New York. Ultimate Spider-Man exists alongside other revamped Marvel characters in Ultimate Marvel titles including Ultimate X-Men, Ultimate Fantastic Four, Ultimate Iron Man, The Ultimates, Ultimate Six and Ultimate Origins. The series is a modernized re-imagining of Marvel's long-running Spider-Man comic book franchise as part of the company's Ultimate Marvel imprint. Ultimate Spider-Man is a superhero comic book series that was published by Marvel Comics from 2000 to 2011. First issue of Ultimate Spider-Man, with the original cover by Joe Quesada